National Institute on Drug Abuse
This five unit, slide teaching packet was designed for use
by health practitioners, teachers, and neuroscientists, to
make presentations to diverse groups ranging from upper level
high school science classes, to middle school students, to
the general public . To assist the presenter, there is a detailed
outline, as well as instructions for creating slides, if these
are preferred over a powerpoint format. For the units with
more sophisticated information, there is also further background
material for the presenter.
The Brain & the Actions of Cocaine, Opiates, and Marijuana
Unit 1 in the series is intended for use with high school
students. The unit is divided into three parts. The first
section introduces the brain and presents some basic neurobiology,
the second introduces the reward pathway and the third presents
the mechanism of action of cocaine, opiates, and marijuana
and how each affects the reward system. In addition there
is an outline for the presenter and also instructions for
creating slides, if these are preferred over a PowerPoint
presentation. The unit is designed to take 30-40 minutes,
without questions. There a total of 25 slides. The presenter
needs to be familiar with neurobiology to use this unit.
The Neurobiology of Drug Addiction
Unit 2 in the series is intended for high school students.
The unit is divided into four parts. The first section includes
an introduction to the neurobiology of the brain. The second
section deals with the mechanisms of reward. The next two
sections deal with the actions of heroin and cocaine in the
central nervous system. The unit is designed to take 30-40
minutes, without questions. There a total of 30 slides. As
with other units in this series, a knowledge of neurobiology
is needed to present this unit.
Understanding Drug Abuse and Addiction: What Science
Unit 3 provides an overview of drug addiction from the perspective
of addiction as "a brain disorder." Beyond presenting the
underlying neurobiology, it also includes material on risk
factors, treatment, prevention, the role of self-help treatment
outcome, and the cost-effectiveness of treatment. The unit
is designed to take 30-40 minutes, without questions. There
are 31 slides. It appears suitable as an overview presentation
with a diverse audiences.
The Neurobiology of Ecstasy (MDMA)
Unit 4 covers the neurobiology of ecstasy, its actions in
the brain, acute and chronic effects, with attention to neurotoxicity,
impact on serotonin transporters. There are 20 slides.
Bringing the Power of Science to Bear on Drug Abuse and
Unit 5 is more elementary than the other units, using analogies
such as the brain as "command central." The long term morbidity
associated with substance use is emphasized and questions
raised as to whether experimentation is worth the risk. There
are 24 slides.
Alcohol Medical Scholars Program
These programs were created by faculty and fellows of the
Alcohol Medical Scholars Program, located at the Medical School
of the University of California at San Diego. The Scholars
Program promotes medical education on alcohol disorders and
other substance abuse-related problems. Each of the units includes
a powerpoint presentation and an accompanying lecture outline,
notes, and references. Review the outline before reviewing
the presentation. There are also several units to assist faculty
in preparing lectures and using electronic media.
Introduction to Diagnosis and Treatment of Alcoholism
by Marc A. Schuckit, MD
This introductory unit is directed to health care workers. It is organized
into 7 sections that cover: definition; natural history and clinical course;
diagnostic criteria; screening process; interventions; treatment process;
and etiology. 18 slides.
by Marc A. Schuckit, MD
This presentation addresses the issue of psychiatric comorbidity associated
with substance use disorders, with special attention to the diagnostic process.
The presentation is organized into 7 sections and covers prevalence, diagnosis,
specific psychiatric conditions (depression, bi-polar disorders, and Anxiety
Disorders) and the role of substance use as self-medication. Data is drawn
from the Collaborative Study on the Genetics of Alcoholism. 13 slides.
Screening and Brief Treatment
by Laura Jean Bierut, MD
This unit is directed to primary care providers and to assist them to identify "at
risk" drinking, I.e. drinking that is associated with increased risk of health
problems, but does not involve alcohol dependence. The format of brief interventions,
and clinical outcomes are described. 16 slides.
Spirituality in Substance Abuse Treatment
by Marianne T Guschwan, MD
This unit addresses the role of spirituality, beginning with definitions,
impact on health, the importance to patients and clinicians, the role in
substance abuse treatment, and research on the role of spirituality in Alcoholics
Anonymous. 20 slides.
Substance Use Disorders and the Family
by Donna L. Londino, MD
The lecture provides an overview of the family influences on substance use
disorders. It is introduced with a brief discussion of the relevance of the
topic, followed by a discussion of genetic aspects, family roles in psychological
development that may influence use; the family''s responses to alcohol and
substance use; and the impact on the family unit of substance abuse problems
on the family unit; and concludes with family aspects of treatment. 22 slides.
The Therapeutic Community as Treatment in Substance Use
by Laura Pieri, MD
This unit considers the therapeutic community (TC) in the treatment of drug
abuse. It defines the therapeutic community; the philosophy; the perspectives
on substance use disorders and the recovery process; the elements of the
therapeutic community as well as program design; and covers treatment outcome
data. 24 slides.
Suicide Attempts in Alcoholics
by Ulrich W Preuss, MD
This unit addresses the relationship of suicide and substance use disorders.
It includes discussion of prevalence, epidemiology, and risk factors. Data
is then presented on a study using data from the Collaborative Study on the
Genetics of Alcoholism, which examines risk factors including demographic
factors, family factors, severity of dependence, and the role of psychopathology.
The Relationship between Alcohol Use Disorders and Nicotine
by Margaret Rukstalis, MD
This presentation addresses the relationship between alcohol use disorders
and nicotine dependence. It covers epidemiology of both disorders, apparent
genetic influences, the levels of co-occurrence, clinical course, morbidity,
treatment including cognitive behavioral therapies and pharmacologic interventions,
and treatment outcome. 31 slides
Medical Consequences of Alcohol and Drug Use Disorders
by Eric B. Raimo, MD
This presentation provides an overview of medical consequences associated
with substance use. It is organized by drug class, and then by body system,
both acutely and as the result of chronic use. 22 slides. Note: There are
a number of graphics and downloading the unit may take extra time.
Genetics of Alcoholism
by Marc Schuckit, MD and John Crabbe, PhD
This unit examines the way different genetically influenced characteristics
increase and decrease the risk of alcoholism. It reviews the types of research,
i.e. family, twin, and adoption studies. Among the characteristics impacting
on risk and which are discussed include risk-related genes (e.g., ALDH2-2)
and broader phenotypes which reflect, at least in part, other risk-related
genes. Examples that are addressed include alcohol metabolizing enzymes;
disinhibition (or impulsiveness/ ASPD/ low P3 amplitude/etc.); a low level
of intensity of response to alcohol; independent psychiatric disorders such
as manic depressive disease and schizophrenia; the opioid system; functioning
of many different neurotransmitter systems. 31 slides.
Level of Response to Alcohol
by Marc Schuckit, MD
This unit examines the phenomenon of level to response to alcohol as a marker
for genetic risk. It also considers level of response in light of other factors
associated with increased risk of alcoholism. Data is drawn from the Collaborative
Study of Genetics of Alcoholism. 34 slides
Medications in the Treatment of Alcoholism
by Vania Modesto-Lowe, MD
Medication has long been used in the management of alcohol withdrawal. Use
of medications as part of treatment and rehabilitation has been more controversial.
This unit reviews the medications that have been used -disulfiram, opiate
antagonists, and acamporsate (structurally similar to neurotransmitter mediators.)
It considers the indications for use, neurobiology, metabolism, and treatment
outcome data. 22 slides.
Fetal Alcohol Syndrome
by Lauren Williams, MD
This unit provides an overview of Fetal Alcohol Syndrome, abnormalities in
the newborn that are attributable to material alcohol use. The presentation
reviews the recent "discovery" of the snydrome; the features and associated
signs; the diagnostic criteria; pathogenesis; epidemiology; risk factors;
clinical course with discussion of secondary disabilities; intervention;
and prevention. 24 slides.
Pharmacology and Neurobiology of Alcohol
by Vijay A Ramchandani, PhD
This unit is organized in two partsx. The first part of the unit reviews
the pharmacokinetics of alcohol - aspects of absorption, distribution and
metabolism - and highlights the factors contributing to the large variability
in alcohol pharmacokinetics. The second part reviews the pharmacodynamics
of alcohol, focusing on the CNS effects, tolerance, why alcohol is an addictive
substance, and the neurotransmitter systems it affects. 21 slides.
Substance Use Disorders in African-Americans
by Jean-Joel Villier, MD
This unit reviews the pattern of alcohol, nicotine, and other drug use among
African-Americans. In general, accross-the-board, African-American use tends
to be lower than that for other racial/ethnic groups. It is noted that blacks
may differ significantly from other groups, making comparisons difficult.
In addition to current and recent use patterns, historical data is also presented.
Risk factors unique to African Americans are noted. 20 slides.
Substance Use in Athletes
by Woodburne O Levy, MD
This unit considers the nature and extent of substance use among athletes.
The types of drugs used range from therapeutic and performance enhancing
drugs to typical drugs of misuse. The historical use of drugs in relation
to athletics is considered, as well as the more recent use. Factors influencing
use are reviewed. There is a review of the substances in each of the major
drug classes along with their consequences and associated mythology. The
unit also covers drug testing, and treatment initiatives. 34 slides.
Alcohol Abuse and Dependence in Gay and Lesbian Populations
by Marty H Hoiness, MD
This unit addresses substance use disorders in gays and lesbians. It covers
prevelence, psychological and societal factors that may increase risk. It
is noted that there are few programs targeted to this population and that
gays and lesbians clients in mainstream programs are unlikely to disclose
their sexual orientation, and are unlikely to be asked. The special risks
related to to HIV/AIDs are noted. 13 slides.
Substance Use Disorders in the Geriatric Patient
by Steven H Madonick, MD
Substance use problems in the elderly too often go unrecognized. The unit
reviews epidemiology, morbidity, substance use disorders most common in the
elderly, diagnostic considerations, and treatment considerations. 30 slides.
by Marc Schuckit, MD
This unit begins with definitions and historical approaches to personality
disorders. It then reviews the application of diagnostic criteria to personality
disorder. It concludes with a brief overview of the different personality
disorders, and highlights those with a particular association with substance
use disorders. 24 slides.
Substance Use Disorders in Physicians
by Christopher J Welsh, MD
This unit is directed to discussing substance use in the health professions.
It begins with epidemiology and also considers some historical examples.
Data is summarized from studies of physicians, health care professionals,
medical students, residents, by medical specialty. There is a presentation
of the natural history and patterns of substance abuse, and discussion of
predisposing factors, including attention to common myths. Warning signs,
interventions, treatment, and treatment outcome are discussed. 32 slides.
Substance Use Disorders among those with Schizophrenia
by Evaristo O Akerele, MD
This unit, directed to healthcare practitioners, addresses substance use
and substance use disorders among those with schizophrenia. It covers prevalence,
consequences of use, etiology, and interventions. 24 slides.
Special Populations: Youth and Women
by Susan F Tapert, PhD
This unit addresses two special populations: women and youth, those from
age 12-18, and those under age 21. It covers epidemiology, risk factors,
assessment, treatment, and treatment outcome. 24 slides.
How to Give a Lecture
by Marianne Guschwan MD and Susan Tapert, PhD
This unit provides very basic and useful pointers for preparing and delivering
a lecture. The unit is divided into three major sections: preparation, delivery,
and the use of audio-visual materials. 18 slides.
by Susan Tapert, PhD
Excellent presentation of the basics in creating powerpoint presentation.
Covers everything from selecting font, color, capitalization, and maximum
content per slide. 29 slides.
How to Organize a Paper or PowerPoint Presentation
by Jean-Joel Villier MD, and Susan Tapert, PhD
This unit provides a model for organizing a paper or powerpoint presentation.
It addresses literature review, taking notes, creating an outline, developing
a draft, references. 16 slides.
- Alcohol as Depicted through Art
- Biochemistry, Pharmacology, and Toxicology of the Alcohols
- Alcohol Use and its Medical Consequences
- Alcohol Use, Abuse, and Dependence
- Pregnancy and the Fetal Alcohol Syndrome
- Alcohol and the Liver
- Alcohol and Alimentary Tract and Pancreas
- Alcohol and the Hematopoietic System
- Endocrine and Metabolic Effects of Alcohol
- Neurological Complications of Alcohol Abuse